tweak
1. slang To use a stimulant drug, especially methamphetamine, for recreational purposes. A: "Hey, Jim, long time no see. Wanna come tweak with us later?" B: "No thanks, man, I gave crank up years ago."
2. slang To behave in a confused, agitated, and psychologically unstable manner as a result of methamphetamine withdrawal. Some junkie on the corner was tweaking so bad that I nearly called an ambulance.
tweak (something) off of (something)
To pluck, pinch, or twist something sharply in order to remove it from something else. She tweaked the back panel off of the gadget to get a look at its circuits. I went over and tweaked the dead heads off of the rose bush. He tweaked a grey hair off of my head.
tweak off
1. To pluck, pinch, or twist something sharply in order to remove it (from something else). A noun or pronoun can be used between "tweak" and "off." She tweaked off the back panel of the gadget to get a look at its circuits. I went over to the rose bush and tweaked a flower off to give to Sarah. He tweaked the grey hair off of my head.
2. To make someone very angry, irritated, or annoyed. A noun or pronoun is used between "tweak" and "off." It tweaks me off so much to be stuck in traffic that I get up extra early to avoid rush hour. I don't know what tweaked him off, but he's been in a foul mood all morning.
tweaked
slang Intoxicated from an amphetamine or methamphetamine. A bunch of kids at the party were getting tweaked on Adderall. He was so tweaked on meth that I thought he was going to hurt someone.
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