1. mod. alcohol or drug intoxicated. If you’re loaded, don’t drive.
2. mod. spiked with liquor; containing much alcohol. There’s a little rum in the eggnog, but it’s certainly not what I would call loaded.
3. mod. having all available accessories. (Said of a car.) Did you want to see a car that’s loaded, or is this to be a budget car?
4. mod. wealthy; loaded with money. Mr. Wilson is loaded, but he is also generous with his money.