vaccinate

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vaccinate (someone or something) with (something

To use a vaccine or similar substance as a means of inoculating a person or animal against infection or disease. Scientists began vaccinating people with weakened or altered forms of the disease. We're experimenting with vaccinating poultry with chemical compounds that trick the birds' immune systems into producing antibodies.
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vaccinate (someone or something) against (something

To use a vaccine or similar substance to produce immunity or resistance in a person or animal against a particular disease. Before we began vaccinating children against tetanus, getting even a minor cut from something rusty could have proved lethal. Farmers who do not vaccinate their livestock against these diseases could face high fines or even jail time.
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vaccinated with a gramophone needle

old-fashioned Disposed to lengthy or endless chatter. A reference to the needle used on a gramophone, a type of early record player, and the needle used to inoculate against infectious disease during vaccination. You'd think he was vaccinated with a gramophone needle from the way he yammers on like that. My mother says I was vaccinated with a gramophone needle, so please stop me if I start rambling.
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vaccinated with a Victrola needle

old-fashioned Disposed to lengthy or endless chatter. A reference to the needle used on a Victrola, a brand of early record players, and the needle used to inoculate against infectious disease during vaccination. You'd think he was vaccinated with a Victrola needle from the way he yammers on like that. My mother says I was vaccinated with a Victrola needle, so please stop me if I start rambling.
See also: needle, vaccinate

vaccinate (someone or an animal) against something

to inoculate or immunize someone or an animal against some disease. They had to vaccinate us against yellow fever. The vet vaccinated the horse against everything that threatened it.
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vaccinate (someone or an animal) with something

to inoculate or immunize someone or an animal with some substance. This time the doctor vaccinated Tom with killed virus. The vet vaccinated the cat with something that would prevent rabies.
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vaccinate against

or vaccinate for
v.
To give someone a vaccination to produce immunity to some infectious disease: The doctor vaccinated the child against measles. The dog has been vaccinated for rabies.
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vaccinated with a Victrola needle

Someone who chatters incessantly. Victrola, a division of R.C.A. Victor, was a brand of phonograph players. Since phono records were played with needles that picked up the sound vibrations in the record's grooves, to be vaccinated with a Victrola needle, as the joke implied, was to be inoculated with the gift of nonstop gab.
See also: needle, vaccinate