vaccinate (someone or something) against (something
To use a vaccine or similar substance to produce immunity or resistance in a person or animal against a particular disease. Before we began vaccinating children against tetanus, getting even a minor cut from something rusty could have proved lethal. Farmers who do not vaccinate their livestock against these diseases could face high fines or even jail time.
vaccinate (someone or an animal) against something
to inoculate or immunize someone or an animal against some disease. They had to vaccinate us against yellow fever. The vet vaccinated the horse against everything that threatened it.
vaccinate againstor vaccinate for
To give someone a vaccination to produce immunity to some infectious disease: The doctor vaccinated the child against measles. The dog has been vaccinated for rabies.