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use someone up
Fig. to use all the effort or talent a person has. His career simply used him up. I used myself up. I'm done. I can't function anymore.
use something up
to consume or use all of something. Use the flour up. I have more in the cupboard. Use up every bit of it. Go ahead.
1. Consume completely, as in The kids used up all their money playing video games. [Late 1700s]
2. Exhaust, tire out, as in I'm totally used up from digging that hole. [Colloquial; mid-1800s]
To consume something completely: We used up all our money on repairs for the house. We used all the gas up before we reached the gas station.