turning point

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*turning point

Fig. a time when things may change; a point at which a change of course is possible or desirable. (Originally nautical. Fig. on the image of a ship approaching a point where a change of course has been planned. (*Typically: be at ~; come to ~; reach ~.) Things are at to a turning point. Bob can no longer afford the payments on his car. I think we have come to a turning point and there ought to be some improvement henceforth.
See also: point, turning
References in periodicals archive ?
Such forward-looking statements include statements regarding, among other things, the efficacy, safety and therapeutic potential of Turning Point Therapeutics' drug candidates, repotrectinib, TPX-0022 and TPX-0046, the results, conduct, progress and timing of Turning Point Therapeutics' development programs and clinical trials including the Phase 1/2 TRIDENT-1 clinical study and the Phase 1 clinical study of TPX-0022, plans regarding future clinical trials, the regulatory approval path for repotrectinib, the strength of Turning Point Therapeutics' balance sheet and the adequacy of cash on hand.
There were no turning points in the match, none on the field and none in the manner in which the Caribbeans have approached their game.
Turning Point's kinase inhibitors are designed to bind to their targets with greater precision and affinity than existing therapies, with a novel, compact structure that has demonstrated an ability to potentially overcome treatment resistance common with other kinase inhibitors.
"We are so grateful for the support from Knights of Columbus and Crystal Lake Brewing," said Turning Point shelter coordinator Mindy Iverson.
10 September 2018 - Kentucky, US-based tobacco products company Turning Points Brands, Inc.
All the money raised at the howdy-themed hootenanny will go directly to the Turning Point service users.
OKLAHOMA CITY Youth Services for Oklahoma County is changing its name to Pivot, with the tagline A Turning Point for Youth.
Biggest turning point: When I started working and doing everything on my own.
San Diego, CA, September 30, 2016 --(PR.com)-- The Turning Point Pregnancy Resource Center (TPPRC), a non-profit pregnancy medical clinic in San Diego, recently announced the details for their upcoming annual fall banquet.
THIRTY thousand people in England are trapped and "forgotten" suffering from both mental health and addiction problems, says charity Turning Point.
ONE of Turning Point's learning disability services - The Cedars in Bulkington - recently held a bake-off attended by local MP Mark Pawsey and Councillor Jill Sheppard, Mayor of Nuneaton and Bedworth.
DEFENDING champion Soren Kjeldsen credits his Irish Open victory as the turning point in his career.
BANKING AND CREDIT NEWS-January 8, 2016-North Castle Partners invests in Turning Point
(AP) -- A Hagerstown Community College student says the school is violating her First Amendment rights by barring her from starting a campus chapter of the conservative youth group Turning Point USA.
Gordon Strachan last night claimed this week's shaming of FIFA can be a huge turning point for world football.