We almost never run randomized controlled trials in the clinic where the control arm is actually 'no treatment'--that is, the patient doesn't undergo any exposure to a sugar pill
, a positive discussion with the provider, nothing.
Food and Drug Administration approved only 19 first-of their-kind drugs--the fewest since 1983--because the others weren't capable of beating the combined power of sugar pills
and the human brain.
By using sugar pills
, saline injections, or even sham surgery, placebo research isolates provision of care from the direct effects of genuine medications or procedures.
Most often, they'll compare the drug against something called a placebo or a sugar pill
. It's basically something that doesn't have a medical effect.
Studies show that a sugar pill
relieves arthritis pain in up to 60 percent of patients.
Twenty-four percent of physicians (160 of the 654 who answered) said it was very likely they'd use the sugar pill
; 34% (221 of 654) said it was moderately likely But 31% (205) said it was unlikely and 10% (68) said definitely not.
Twenty-four percent of physicians (160 of the 654 who answered these questions) said it was very likely they'd use the sugar pill
; 34% (221 of 654) said it was moderately likely.
These were followed by a study in which 421 seriously behaviorally disturbed patients were assigned to receive either atypical antipsychotic drugs or a placebo (sugar pill
) over an eight-week period.
Placebo: a pill or substance that has no effect on the body, such as a sugar pill
. It is often compared to a real medication to see what the real effect of the medication might be.
They emphasize that, with the exception of one study in which new cancer diagnoses were more frequent on pravastatin than on a sugar pill
, all large prospective randomized statin trials have shown no difference in the risk of cancer among people taking statins versus those taking a sugar pill
For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill
), according to results published online on March 28, 2007 in the New England Journal of Medicine.
The diminutive, white sugar pill
is easy to feed--just a quick drop from the vial cap into his mouth and first aid is done.
In each study, patients were assigned at random to receive either Zelnorm[R] or a sugar pill
Schering-Plough had been touting the safety of Claritin for years; the company's ads explicitly state that the side effects are those of a sugar pill
. Robert Seidman, WellPoint's chief pharmaceutical officer, reasoned, "If they're marketing these like candy, then they should be sold like candy."