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1. To grow, rise, or increase very quickly or dramatically. Wow, you kids have really shot up since you were here last summer! Stocks in the company shot up when they announced the impressive sales figures for their latest product. Rental prices have started shooting up in this area over the last couple of years.
2. slang To use recreational drugs intravenously, especially heroin. This is a nasty part of town; you can find someone shooting up around just about every corner.
1. Severely wounded by gunfire; see shoot up, def. 2.
2. Drugged; see shoot up, def. 3.