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screw (one) over
To con, swindle, cheat, or unfairly deprive one; to put one at a disadvantage or in a difficult position, especially in an unfair or selfish manner. You should have won that game, but the referee really screwed you over! Tom really screwed us over when he quit in the middle of the project!
screw someone over
Sl. to give someone a very bad time; to scold someone severely. Those guys really screwed you over. What started it? Don't think you can screw over me and my friends. I won't let you.
Vulgar Slang To treat someone unfairly; take advantage of someone: The billing department really screwed me over. The new management screwed over the staff with their rigid policies.