The seeds were continuously rinsed in 30% (v/v) commercial bleach (HES) with 1-2 drops of Tween-20 for 15 minutes followed by 3 times rinses with
sterile distilled water.
The chitosan rinse was shown to be superior to both CHG and EO rinses with
regard to MIC and adherence qualities.
It is likely that these rare events have led to preclinical and, in particular, in vitro testing of oral rinses with the aim of understanding if oral rinses have an antimicrobial activity and whether they are ultimately cytotoxic, at least under in vitro conditions.
Here we investigated a dozen oral rinses with regard to their cytotoxic and antimicrobial effects on oral cells and bacteria.
With regard to oral rinses with antimicrobial activity, those containing CHX (#3, #8) were more potent compared to those containing CPC (#9, #10) and those containing other components (#6, #7, #11, and #12).
The same technique was used for the 2nd and 3rd experimental period with the other two mouth rinses with
an identical wash out phase of two weeks.
The only systematic review (meta-analysis) of six-month clinical trials of mouth rinses with
agents to control plaque and gingivitis was published in the Journal of the American Dental Association in 2006.
Harold Katz LLC, which is credited with starting the premium oral rinse sector when it introduced Thera-Breath in 2000, has extended its line of oral rinses with
the introduction of PerioTherapy, a product aimed at healing damaged gums.
While many patients associate mouth rinses with
breath issues, Gutierrez discusses breath issues as a side effect of health problems so as to not make the patient self-conscious.