Kaplan-Meier analysis and the log-rank test also showed that the first relapse was significantly earlier in the frequent relapsers
than in the infrequent relapsers
Conclusion: Majority of the sustained responders had disease eradication, but non responders and relapsers
should be followed for any evidence of cirrhosis.
Among these, 100 (91.7%) patients had never achieved undetectable HCV RNA (qualitative polymerase chain reaction [PCR] testing) during the first treatment, and were, thus, non-responders, while 9 (8.3%) patients had shown undetectable HCV RNA during the therapy, but had become HCV RNA positive after discontinuing medication and were, thus, relapsers
. Genotype 1 was seen in 29 (26.6%) patients and Genotype 3 in 78 (71.6%).
A chronic relapser
might need this amount of time to emerge out of what the author refers to as a "fog."
Based on this description of the chronic relapser
, it is clear that there are common characteristics in the profile of these individuals.
Taking into account the mean score of the EQ-5D index and the EQ VAS, the sociodemographic profile of the relapsers
who present worse HRQoL is characterized as being female, being 50 or older, lower educational level, being divorced/separated or widowed, and not to work.
One out of four primarysteroid resistant nephrotic syndrome patients and five out of six steroid-dependent nephrotic syndrome patients became infrequent (5) or frequent (1) relapsers
And quitters can become relapsers
. A 1994-2011 study of 2961 HIV-positive and 981 HIV-negative women in the Women's Interagency HIV Study (WIHS) found that smoking prevalence in this largely black and Hispanic cohort waned from a high of 57% in 1996 to a low of 39% in 2011.3 Among 1622 women who smoked at their first study visit, 316 (19.5%) quit for a hefty median of 16.5 years.
The amount of both CC and GG homozygotes was diminished in these frequent relapsers
. The allele distribution between groups with over and under five relapses showed no difference.
Luszczynska A, Sutton S (2006) Physical activity after cardiac rehabilitation: Evidence that different types of self-efficacy are important in maintainers and relapsers
. Rehabilitation Psychology 51: 314-321.
Researchers found that a decrease in slow alpha activity in alcoholics is more pronounced in relapsers
than in those who maintain abstinence (Saletu-Zyhlarz et al.
58% of patients presented for the first time, about 24% of patients were frequent relapsers
and 18% were infrequent relapsers
(2003b) reported that subjects who relapse reported more severe NWS during smoking abstinence than did non relapsers
This benefit directly improves the lives of chronic relapsers
, arguably the patients who need treatment the most.