Since then we propose to
inquire what civil society is of all others best for those who have it in their power to live entirely as they wish, it is necessary to examine into the polity of those states which are allowed to be well governed; and if there should be any others which some persons have described, and which appear properly regulated, to note what is right and useful in them; and when we point out wherein they have failed, let not this be imputed to an affectation of wisdom, for it is because there are great defects in all those which are already 'established, that I have been induced to undertake this work.
I propose to
tell you--in the first place--what is known of the manner in which your cousin met his death; appending to the statement such inferences and conclusions as we are justified (according to my opinion) in drawing from the facts.
I shall surprise our friend Maston, then, by stigmatizing his calculations as timid; and I propose to
double his 800,000 pounds of powder."
Applicants may propose to define critical components in the signature, to confirm that the selected components continue to provide the desired clinical information and to develop robust assays for measuring those components.
Applicants may propose to evaluate signatures the have previously been identified using analytical technologies such as, but not limited to, gene expression microarrays, SAGE, multiplex PCR or any of a large number of protein analysis technologies.
The private investment fund activities in which Notificants propose to
engage consist of serving as the investment adviser to and the general partner of, and holding and placing equity interests in, certain investment funds that invest only in securities and other instruments that Notificants would be permitted to hold directly under the BHC Act ("private investment funds").
Applicants may propose to
obtain tissues from a previous collection or prospectively, as long as the specific alms proposed can be accomplished within the period of the grant award.