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1. To quit or give up something due to exhaustion or fatigue. I thought I would be able to make it to the end of the race, but I pooped out after the fifth mile. You can't keep working the team like this, or they'll poop out and the project will never get finished at all.
2. To cause someone become exhausted or fatigued. In this usage, a noun or pronoun can be used between "poop" and "out." Running around with my grandson all afternoon really pooped me out! I think the change in elevation during the hike pooped out my father-in-law quicker than he was expecting.
Very exhausted or fatigued, especially from physical exertion. I was really pooped out after running around with my grandson all afternoon! Don't hike too far or you'll be too pooped to hike all the way back.
1. mod. exhausted; worn-out. (Said of a person or an animal.) The horse looked sort of pooped in the final stretch.
2. mod. alcohol intoxicated. He’s been drinking all night and is totally pooped out.