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overdose on (something)

To experience an extreme, life-threatening physical reaction to some narcotic, especially heroin, opioids, cocaine, or amphetamines. I thought I was overdosing on my medication when I started losing consciousness like that. My brother eventually overdosed on morphine after getting addicted to it following his surgery.
See also: on, overdose

overdose (someone) (on something)

 and overdose someone with something
to give someone too much of some substance, usually a drug. The police say he overdosed on heroine. Sam overdosed his sister on the cough medicine. She overdosed herself with aspirin.
References in periodicals archive ?
The office has distributed 16,000 doses of naloxone to emergency responders, developed standards for syringe exchange programs, set up an Office of Drug Control Policy and worked with a national group that represents health officials to share West Virginia's opioid-fighting efforts, such as the analysis of people who overdosed.
As Christopher, a 38-year-old man who had overdosed on a mixture of alcohol and injected heroin, explained:
During the 6 months before the interview, 95% of respondents witnessed an overdose and 42% overdosed themselves.
I have run into quite a few that have overdosed on Tylenol,'' Alpern said.
Ralph Young, 40, who died of a heroin overdose, was buried on Friday, and four months ago, David Wilson, 17, overdosed on the drug.
The late, legendary singer Prince overdosed last week from a prescription medication called Percocet, according to a (http://www.
But when Belushi overdosed in 1982 after taking a speedball - a risky combination of cocaine and heroin - drugs began to lose their cachet, if not their seductive chemistry.
8% of the HODDs occurred in public settings where a passerby might have found the person who had overdosed.
Sophie was accidentally overdosed because her parents and physician were unaware that grape-flavored infant Tylenol is 3-1/2 times stronger than children's Tylenol, according to a lawsuit they filed against the doctor and McNeil.
Super-model Naomi Campbell returned to work Monday and was feeling ``very well'' after an adverse reaction to antibiotics, her agency said, denying reports she had overdosed on drugs.
The family's lawyer, Kevin Kearse, said Harter overdosed on a prescription drug for anxiety.