off (one's) meds

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off (one's) meds

1. Literally, not taking one's prescribed medications. I've been able to think more clearly after going off my meds—my mind doesn't feel as foggy. I knew as soon as she walked in that she was off her meds—she never acts that way when she's on her regimen.
2. Crazy or insane. Potentially offensive due to the implication of mental illness. She's off her meds if she thinks she can come in here and talk to me in that tone of voice! When Paul suddenly decided to pick up and move across the country, everyone said he must be off his meds.
See also: med, off
References in periodicals archive ?
They actually say hello to each other in the street and when you're standing in a queue it's quite okay to strike up a conversation without looking like you're off your meds.
That will shrink your tumors, clear your arteries, lubricate your joints, improve your sleep, wean you off your meds, and cut the nation's runaway health care bill by 70 percent" But Fulkerson's documentary about the threats posed to our personal and national health by a Western diet rich in animal and dairy products isn't funny.
Crushing chords, relentless backbeat, a structure that is absolutely Byzantine, seductive vocals, half-human growls, frantic metal riffs you can play only when you're totally off your meds.