off (one's) meds

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off (one's) meds

1. Literally, not taking one's prescribed medications. I've been able to think more clearly after going off my meds—my mind doesn't feel as foggy. I knew as soon as she walked in that she was off her meds—she never acts that way when she's on her regimen.
2. Crazy or insane. Potentially offensive due to the implication of mental illness. She's off her meds if she thinks she can come in here and talk to me in that tone of voice! When Paul suddenly decided to pick up and move across the country, everyone said he must be off his meds.
See also: med, off
References in periodicals archive ?
Maria Bello, as Sophie, is as fidgety as someone off their meds.
It's when they fall off their meds that they don't.
When patients were taken off their meds for four weeks, the number of unprotected T-cells still in the body fell dramatically, whereas the modified T-cells appeared protected and could still be found in the blood several months later.
But one study presented at the conference documented a group of patients in France who were treated early, went off their meds, and have seen the level of HIV in their bodies remain low.
Lauderdale, about her deceased kin, voicing her fears about the mentally ill on the streets and off their meds.