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Someone who is overcome with anxiety, apprehension, or nervousness. Where have you been all night? I've been a nervous wreck waiting for you to come home! I'm going to be a nervous wreck waiting to hear back from the doctor about the test results.
An individual suffering from extreme agitation or worry, as in Pat was a nervous wreck until her mother arrived at the wedding. This expression is nearly always used hyperbolically. [Colloquial; c. 1900] Also see basket case.