1. To move in a continuous, aimless manner. I know you're still feeling woozy, but try moving about a little bit. Would you quit moving about in bed like that? I'm trying to sleep!
2. To cause or compel someone or something to move from one place or point to another. In this usage, a noun or pronoun is used before or after "about." I rolled my ankle funny, Doc, and now it hurts to move it about. I wish you wouldn't move about the furniture like that—I have it decorated in a particular way! The teacher moves us about each month so that we sit next to different students throughout the year.
See also: move