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off (one's) meds

1. Literally, not taking one's prescribed medications. I've been able to think more clearly after going off my meds—my mind doesn't feel as foggy. I knew as soon as she walked in that she was off her meds—she never acts that way when she's on her regimen.
2. Crazy or insane. Potentially offensive due to the implication of mental illness. She's off her meds if she thinks she can come in here and talk to me in that tone of voice! When Paul suddenly decided to pick up and move across the country, everyone said he must be off his meds.
See also: med, off

off one’s meds

phr. acting strangely. Man, what a temper! Must be off her meds.
See also: med, off
References in periodicals archive ?
Barry Corkern, Contour Med's interim CEO, declined to comment on the bankruptcy last week.
The research revealed significant changes in the profile of inpatients at The MED. Data were compared from the period of July-September 2004 to data from that same period of July-September 2005.
Donde el [Z.sub.PT] es el punto de chequeo de elevacion, [Z.sub.MED] es la elevacion del MED en el punto de chequeo y n es el numero de puntos de chequeo.
Hoggets (2,590), overall av 124.4p; standard av 120.3p; med av 125.5p; heavy av 115p; overweight av 105.6p.
Bar Med asks people to wear smart casual clothes at all times, so you won't be able to blag your way in wearing a tracksuit or training shoes!
First, the failure to do background checks on med school applicants is scandalous.
He profiles med students who write poetry and think big thoughts about the relationship between behavior and health.
Navigation through Med TechNet is completely menu driven.
The arrival of ESF at Club Med Ski School will significantly raise the standards of skiing experience in Mainland China.
The family of employees at MED + work diligently every day to serve their community with the best possible service they can provide.
signed a contract with Club Med this month to begin construction of the facilities next year and estimates a budget of NT$2.2 billion (US$75 million) for the project.
Selon l'Autorite Marocaine des Marches des Capitaux (AMMC), la societe Aliken, representee par Sefrioui, a declare le 5 juillet 2017, avoir acquis sur le marche central, le 3 juillet 2017, 814.037 actions Med Paper, au cours moyen pondere de 28,64 dirhams franchissant a la hausse les seuils de participation de 5%, 10% et 20% dans le capital de ladite societe.
Q biotype whiteflies, more properly known as Bemisia tabaci Mediterranean (MED) and classified as B.
Recently the Office of Medical Services was designated the Bureau of Medical Services (MED).
NBC TV series "Chicago Med" returns in 2017 with brand new episodes featuring complicated cases and difficult decisions.