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off (one's) meds

1. Literally, not taking one's prescribed medications. I've been able to think more clearly after going off my meds—my mind doesn't feel as foggy. I knew as soon as she walked in that she was off her meds—she never acts that way when she's on her regimen.
2. Crazy or insane. Potentially offensive due to the implication of mental illness. She's off her meds if she thinks she can come in here and talk to me in that tone of voice! When Paul suddenly decided to pick up and move across the country, everyone said he must be off his meds.
See also: med, off

off one’s meds

phr. acting strangely. Man, what a temper! Must be off her meds.
See also: med, off
References in periodicals archive ?
This leading edge technology gives Club Med unparalleled reach in the global marketplace.
New promotion-oriented marketing resulted in programs aimed at senior citizens (Forever Young), singles and couples (Wild Card) and families (Kids Free Weeks plus Family Escape), thus encouraging consumers from an even broader market base to try a Club Med vacation.
said that the club would test the market for Vietnam this coming winter by offering cruises aboard Club Med 2, departing from Singapore and calling at Vietnam en route to Hong Kong.
The overriding decision to attempt this corporate conversion in marketing strategy centered on the marketing reach of the Med Gen product lines, which exceeds $100 billion and the tremendous cost involved in selling major chains and discount stores.
As a precursor to its investment in TV and Print advertising programs, Med Gen has completed a thorough study to support any claims it makes regarding the weight loss program the company hopes will contribute significantly to its revenues and earnings this year.
Increasing the reach of our products is an important part of our building plan," said Paul Mitchell, Med Gen's President and COO.
In answer to investor/shareholder questions, Paul Kravitz, Med Gen Chairman and Chief Executive explains the following.