marrow

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chill (one) to the bone

1. To make or be very cold. In this usage, a pronoun does not have to be used between "chill" and "to." After shoveling snow for hours, I am just chilled to the bone. The wind from the mountain chilled us to the bone.
2. To cause one to be very scared. In this usage, a pronoun is usually used between "chill" and "to." The sight of blood just chills me to the bone.
See also: bone, chill

chill (one) to the marrow

1. To make or be very cold. A pronoun does not have to be used between "chill" and "to." ("Marrow" is the soft tissue found inside bones.) After shoveling snow for hours, I am just chilled to the marrow. The wind from the mountain chilled us to the marrow.
2. To cause one to be very scared. In this usage, a pronoun is usually used between "chill" and "to." The sight of blood just chills me to the marrow.
See also: chill, marrow

chilled to the bone

Of a person, very cold. After shoveling snow for hours, I am just chilled to the bone.
See also: bone, chill

be chilled to the marrow

To be very cold. ("Marrow" is the soft tissue found inside bones.) After shoveling snow for hours, I am just chilled to the marrow. We were chilled to the marrow after being subjected to the wind from the mountain.
See also: chill, marrow

to the marrow

Through and through; thoroughly; in every manner or respect. The fellow is stubborn to the marrow; he won't even listen to my plan the whole way through! Though he grew up in America, Henry is still British to the marrow.
See also: marrow

*chilled to the bone

Fig. very cold. (*Typically: be ~; get ~.) I got chilled to the bone in that snowstorm. The children were chilled to the bone from their swim in the ocean.
See also: bone, chill

chilled to the bone

Also, chilled to the marrow. Extremely or bitterly cold, as in After skiing in the wind for five hours straight, I was chilled to the bone. These hyperboles replaced the earlier idea of one's blood freezing and are more picturesque than the current synonym frozen.
See also: bone, chill

chilled to the marrow

or

frozen to the marrow

mainly BRITISH
If you are chilled to the marrow or frozen to the marrow, you are very cold. Note: `Marrow' is the fatty substance inside the bones of a person or animal. She was chilled to the marrow and wet through.
See also: chill, marrow

to the marrow

You can use to the marrow to show how strong someone's feelings or beliefs are. Note: `Marrow' is the fatty substance inside the bones of a person or animal. He was a Democrat to the marrow. Note: Sometimes, people use the longer expression to the marrow of your bones. Some films chill you to the marrow of your bones.
See also: marrow

to the marrow

to your innermost being.
Marrow is the soft, fatty substance found in the cavities of bones.
1994 Maurice Gee Crime Story Moral corruption, the lawyer said. Men who are greedy to the marrow of their bones.
See also: marrow

chill somebody to the ˈbone/ˈmarrow

frighten somebody very much: His threat chilled her to the bone.
Marrow is a soft substance that fills the hollow parts of bones.
See also: bone, chill, marrow, somebody

chilled to the bone

Very cold indeed. This hyperbole for feeling cold replaces the older idea of one’s blood freezing. Thus Shakespeare wrote of Pericles, after he was shipwrecked, “A man throng’d up with chill; my veins are cold” (Pericles, 2.1). This thought persisted well into the nineteenth century, appearing in poems by Tennyson (“Till her blood was frozen slowly,” in “The Lady of Shalott”) and Lawrence Binyon (“In the terrible hour of the dawn, when the veins are cold,” in Edith Cavell).
See also: bone, chill
References in periodicals archive ?
All patients who underwent simultaneous bone marrow aspiration and trephine biopsy (n=443) were included in this study.
After taking ethical approval and written informed consent about 0.5 to 1.0 cc bone marrow aspirates was taken from posterior superior iliac spine by using Salah's needle and employing standard technique.
A total of 443 cases underwent simultaneous bone marrow aspiration and trephine biopsy.
" If a ' full match' is not found, the bone marrow can be toxic for the recipient.
We treated him twice but the results were not encouraging, so we thought of going in for a half- matched bone marrow transplant," Dr Bhurani said.
A bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells.
Various studies have been done to determine marrow involvement in solid tumours 5,6 whereas only few studies have analysed marrow involvement in neuroblastoma and its correlation with hematological profile.7-9 This study aimed at determining the frequency and pattern of marrow involvement in neuroblastoma in pediatric cases at initial presentation, and its correlation with hematological parameters.
Diagnosed cases of neuroblastoma on hematoxylin and eosin stain along with immunohistochemistry for round blue cell tumour panel using Synaptophysin, Neuron specific Enolase, Desmin, Myogenin, CD45 and WT1 and referred for marrow biopsy from January 2016 to December 2017 were selected for this study.
Bone marrow aspiration and core biopsies were performed from posterior superior iliac spine and in children under 18 months of age only bone marrow aspirates were obtained from tibia.
A retrospective, morphologic review and an electronic medical-record review were performed for the 40 bone marrow cases in this study.
Bone marrow biopsies obtained by the single-needle technique were similar in length (mean, 0.99 cm) to biopsies obtained by the 2-needle technique (mean, 1.17 cm).
For the 1-needle technique, the biopsy quality was assessed as having moderate disruption of bone marrow areas with loss of marrow cells and crush artifacts (+++) for 50% (10 of 20) of the cases, mild disruption (++) for 35% (7 of 20) of the cases, and minimal disruption (+) for 15% (3 of 20) of the cases.
Normal bone marrow morphology was seen in 16 (5.7%) cases.
Presence of megaloblastic anaemia can usually be suspected from examination of peripheral blood with oval macrocytes being characteristic but examination of bone marrow aspirate is crucial in the diagnoses.
Out of six cases of diagnosed Hodgkin\'s disease with pancytopenia five had marrow infiltration detected only on trephine, as has been reported in previous studies17 there was only one case of Non Hodgkin\'s lymphoma with pancytopenia, and marrow infiltration was not detected.