louse something up

louse up

To ruin, spoil, mess up, or bungle someone or something. A noun or pronoun can be used between "louse" and "up." Her sudden decision to quit in the middle of the project really loused us up. I am not letting your crummy attitude louse up my vacation—if you want to be grouch, you can go somewhere else and do it alone!
See also: louse, up
Farlex Dictionary of Idioms. © 2015 Farlex, Inc, all rights reserved.

louse something up

tv. to botch something up. Please don’t louse the typewriter ribbon up this time.
See also: louse, something, up
McGraw-Hill's Dictionary of American Slang and Colloquial Expressions Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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