1. To depart some place while accompanying or being accompanied by someone. He arrived with Stacey, but I think he left with Lacey. A: "Where did you end up last night?" B: "I left with Mark and the guys to grab a bit to eat."
2. To allow someone or something to be in the custody of someone else. In this usage, a noun or pronoun can be used between "leave" and "with." We're leaving the kids with my mother-in-law this weekend. Can I leave my bike with you while I run in to buy some milk?
3. To allow someone to take responsibility for something. In this usage, a noun or pronoun can be used between "leave" and "with." A: "I'm just not sure how to tackle this problem." B: "Leave it with me, I'm sure I can think of something." Do you mind if I leave th9is project with you? I just have too much on my plate at the moment.
leave someone or something with someone or something
to allow someone or something to remain with someone or something. Can I leave Jimmy with you while I shop? Do you mind if I leave my papers with the committee, just in case they have time to look at them?
leave with someone
to depart in the company of someone. I left with Frank early in the evening and did not see what happened to Tom and Edna. Mary is gone. She left with Gerald.