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1. adjective Of or being the most advanced position, practice, or technology in a given area, activity, or endeavor. Sometimes hyphenated. Scientists at the local university are pioneering the nation's most leading-edge cancer research. The company has released some of the most leading-edge smartphones in the world.
2. noun The most advanced position, practice, or technology in a given area, activity, or endeavor. The work their organization is doing at the moment is the leading edge of public health. Anthony's fascination with gadgetry always has him at the leading edge of the latest technology.