know (something) like the palm of (one's) hand

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know (something) like the palm of (one's) hand

To be extremely familiar with a particular subject, place, or piece of media. I've read this book so many times that I know it like the palm of my hand at this point. You should ask Samantha for directions—she knows this town like the palm of her hand.
See also: hand, know, like, of, palm

know someone or something like the palm of one's hand

 and know someone or something like the back of one's hand; know someone or something like a book
to know someone or something very well. Of course I know John. I know him like the back of my hand. I know him like a book.
See also: hand, know, like, of, palm