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interact with (someone or something)

1. To engage with someone. Turn off your video game and go interact with your cousins, please.
2. To interfere or react with something (often of drugs), triggering a negative effect on someone. Will this medication interact with anything else Mom's taking? Caffeine is known to interact with this drug and cause tachycardia.
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Farlex Dictionary of Idioms. © 2022 Farlex, Inc, all rights reserved.

interact with someone

to converse with and exchange ideas with someone. In act two, I want Terri to interact with Amy a little more. They act as if they never even met each other. The students will interact with one another in their study projects.
See also: interact

interact with something

to have a reciprocal action with something; to react with something. (Often refers to the negative consequences of interaction.) Witt this drug interact with coffee? This drug will not interact with your current medication.
See also: interact
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs. © 2002 by The McGraw-Hill Companies, Inc.
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