1. slang To ignore someone until they go away, rather than directly expressing one's disinterest, especially in virtual communications. This phrase is often applied to failed love connections. That guy I went out with last week kept texting me, but I just wasn't interested, so I had to ghost him.
2. slang To kill someone. The boss told Ray to ghost the informant.
tv. to kill someone. Mooshoo threatened to ghost the guy.