Lombardi, Gundersen, Zammett, Walters, and Morris (1988) compared IV catheters flushed with heparin and catheters flushed with saline in a sample of 74 pediatric patients, age 4 weeks to 18 years.
The investigators demonstrated that for 18- to 24-gauge catheters, normal saline was as effective as heparin in maintaining patency, but they did have more problems (e.g., infiltration, phlebitis, and clotting) than those flushed with heparin.
However, for 120 pediatric patients with 24-gauge catheters, the median length of duration of patency in IV catheters flushed with heparin was significantly greater (p = .03) than in catheters flushed with saline (34 hours and 22 hours respectively).
Results indicated that there was a longer duration of IV catheter patency and less tenderness at the catheter site in those PIIDs flushed with heparin.
The purpose of this study was to determine if there was a significant difference in the duration of patency in 24-gauge PIIDs when flushed with normal saline compared to heparinized saline 10 u/ml.
Catheters were flushed with only one solution type for the life of the catheter.
In this method, organs are kept at 0[deg.] to 4[deg.]C after being flushed with certain fluids.
When the organs of a body are to be preserved, says Outhard, the whole body ends up being flushed with preservation fluids.
Right now, the best-performing 1.6 gallon toilets can eliminate 1,000 grams or more of waste cleanly in a single flush--far more than many of the older 3.5 gallons toilet models that flushed with
more than twice the volume of water."
Catheters not used for medication administration were flushed with one of the study solutions every 8 hours.
However, a significant increase in longevity was found in the 24-gauge catheter group when flushed with heparin compared to normal saline (Danek E; Noris, 1992).
There was no statistical difference between the mean period of patency for catheters flushed with heparin (43.61 hours) and those flushed with normal saline (41.02 hours).
IV locks flushed with saline lasted as long as those flushed with heparin.
In the remaining 104 subjects, no difference was found in the longevity of IV catheters flushed with heparin versus those flushed with saline.
In contrast to earlier findings, the investigators found longer patency times in catheters flushed with heparin and more clotting problems in catheters flushed at 8 hour intervals compared with those flushed at 4 hour intervals.