4 Non-diarrheal CD (NDCD) has variable presentation including failure to thrive
, short stature, refractory anemia, rickets, vomiting and recurrent oral ulcers.
Failure to thrive
is an important presentation in pediatric age group CD patients.
In our patient, although the aldosterone and renin were not measured because of lack of adequate sample, the combination of failure to thrive
, marked electrolyte imbalance at presentation, urinary tract anomaly with infection due to GBS, normalization of electrolytes with fluids and antibiotic treatment, slightly high Cortisol concentration and multiple normal 17-OHP measurements, and persistent electrolyte normalization after discharge, is consistent with PHA type 3 caused by UTI and/or malformation.
Despite maximal antiproteinuric therapy, the patient remained highly proteinuric with failure to thrive
Major clinical presentation in this study was abdominal distension and failure to thrive
Symptoms and signs of vitamin B12 deficiency appear between the age of 4 and 12 months and include failure to thrive
, lethargy, hypotonia, and arrest or regression of developmental skills.
Frequency of different clinical features in descending order revealed that chronic diarrhoea, abdominal distension, iron deficiency anaemia, failure to thrive
, pallor and rickets were present in 38 (73.
Later, in the 1960s, failure to thrive
was referred to as reactive attachment disorder in the Diagnostic and Statistical Manual classification system, reflecting its connection with developmental delay and mental health problems (Schwartz, 2000).
The study finds that failure to thrive
can be tied to three major economic factors worldwide.
The gastrointestinal tract is often involved secondary to occlusion of the pancreatic and biliary ducts with thickened secretions leading to chronic malabsorption and failure to thrive
In the 15 patients with CD, the most common mode of presentation was gastrointestinal, accounting for 7/15 patients and comprising of diarrhea (6), abdominal pain (4), weight loss (1): followed by type 1 DM (5/15), clinical anemia (5/15), short stature or failure to thrive
(4/15) and hypothyroidism (2/15), one patient had both type 1 DM and hypothyroidism, Table 1.
These manifestations are in turn related in the genesis of different geriatric syndromes like frailty, falls, cognitive decline, and geriatric nutritional syndromes like failure to thrive
and anorexia of aging (2).
Consultants from North America, Brazil, and Australia consider aspects of the profession, including communication and counseling skills, the parental role, maternal mental health and employment, and vulnerable populations; professional development, including education, research, and legal issues; breastfeeding anatomy, physiology, nutrition, and biochemistry; techniques, including for preterm infants, twins and multiple births, and mothers with disabilities; breastfeeding technology and equipment; and problem solving, with discussion of breast pathology, hyperbilirubinemia and hypoglycemia, maternal illnesses, insufficient milk production, and slow weight gain and failure to thrive
For instance, a child suffering from thalassemia could have endocrine complications such as iron over-dose or could also suffer failure to thrive
and later in life infertility or diabetes," he explained.
Symptoms may include heartburn, dysphagia, vomiting, failure to thrive
, abdominal pain, and impaction of food.