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Hemophilia (or haemophilia) B, a blood-clotting disorder in which a mutation of the Factor IX gene leads to a deficiency of Factor IX (or Christmas factor), a serine protease of the coagulation system. Both the factor and the disease are named for Stephen Christmas (not the holiday), the first patient discovered to have the condition in 1952. We haven't let our daughter participate in any more physical sports since she was diagnosed with Christmas disease last year.
desperate diseases must have desperate remedies
Extreme and undesirable circumstances or situations can only be resolved by resorting to equally extreme actions. I know that the austerity measures introduced by the government during the recession are unpopular, but desperate diseases must have desperate remedies.
down with (an illness)
Sick with a particular illness, which is named after "with." I've been down with the flu all week and have barely gotten out of bed.
See also: down
the disease to please
A constant need to make others happy. I think you're miserable because you have the disease to please. Try doing what makes you happy instead.
1. To rid or free oneself from someone or something that one finds aggravating, upsetting, or annoying. A noun or pronoun can be used between "shake" and "off." My little brother has been following me around all day. I need to shake him off. He had a hard time shaking off the feeling that someone was spying on him.
2. To shake something in order to get something off of it. A noun or pronoun can be used between "shake" and "off." I had to shake off the old tarp to get the bugs and dirt off of it. Shake the blanket off before you lay it out.
3. To dislodge or get rid of something by shaking. A noun or pronoun can be used between "shake" and "off." He tried to shake the tick off, but it had dug itself into his skin. Don't shake the mud off inside—go out in the back yard and do it!
4. To recover from or fend off a disease or illness, especially a minor one. A noun or pronoun can be used between "shake" and "off." I've got to shake this tummy bug off—I can't afford to be sick before our big meeting! I've had this cold for nearly a week that I just can't seem to shake off! I could feel myself getting sick, but I managed to shake it off.
the British disease
That which supposedly plagues British people, government, or society. Used especially in reference to an inability or unwillingness to be as productive as possible. The real British disease is not complacency or unrest, but the desire to achieve short-term goals at the cost of investing in long-term, sustainable economic policies.
A habit of unintentionally saying foolish, tactless, or offensive things. He has foot-in-mouth disease, especially when he's forced to speak for too long, so try to get him off stage as soon as possible. Oh man, do I have foot-in-mouth-disease—I just congratulated Sarah's sister on being pregnant. She isn't.
Desperate diseases must have desperate remedies.
Prov. If you have a seemingly insurmountable problem, you must do things you ordinarily would not do in order to solve it. Fred: All my employees have been surly and morose for months. How can I improve their morale? Alan: Why not give everyone a raise? Fred: That's a pretty extreme suggestion. Alan: Yes, but desperate diseases must have desperate remedies.
(the) disease to please
an obsessive need to please people. I, like so many, am afflicted with the disease to please. I am just too nice for my own good.
*down with a disease
ill; sick at home. (Can be said about many diseases. *Typically: be ~; Come ~; get~.) Tom isn't here. He's down with a cold. Sally is down with the flu.
the tendency to say the wrong thing at the wrong time. I suffer a lot from foot-in-mouth disease. Well, Ralph has foot-in-mouth disease again.
shake a disease or illness off
Fig. [for the body] to fight off a disease or illness. I thought I was catching a cold, but I guess I shook it off. I hope I can shake off this flu pretty soon.
shake someone or something off
Fig. to get rid of someone; to get free of someone who is bothering you. Stop bothering me! What do I have to do to shake you off? I wish I could shake off John. He's such a pest!
shake something off
to get rid of something that is on one by shaking. (See also shake a disease or illness off.) I tried to shake the spider off. The dog shook off the blanket Billy had put on him.
foot in one's mouth, put one's
Say something foolish, embarrassing, or tactless. For example, Jane put her foot in her mouth when she called him by her first husband's name. This notion is sometimes put as having foot-in-mouth disease, as in He has a bad case of foot-in-mouth disease, always making some tactless remark. The first expression dates from about 1900. The variant, dating from the mid-1900s, is a play on the foot-and-mouth (sometimes called hoof-and-mouth) disease that afflicts cattle, causing eruptions to break out around the mouth and hoofs.
Free oneself or get rid of something or someone, as in I've had a hard time shaking off this cold, or She forged ahead, shaking off all the other runners. It is also put as give someone the shake, as in We managed to give our pursuers the shake. The first term dates from the late 1300s; the slangy variant dates from the second half of the 1800s.
the British diseasea problem or failing supposed to be characteristically British, especially (formerly) a proneness to industrial unrest. informal
1. To shake something so as to dislodge what is on it: We shook off the picnic blanket to get rid of the grasshoppers. I picked up the beach towel and shook it off.
2. To get rid of something by shaking: The dog climbed out of the creek and shook off the water. I shook the snow off my jacket and hung it up.
3. To free oneself of something; get rid of something: We shook off our fear and proceeded into the dark cave. The injured player shook the pain off and continued to play.
n. the tendency to say the wrong thing at the wrong time. Well, Ralph has foot-in-mouth disease again.
white man’s disease
n. the inability to jump in basketball. You break your leg, Walter? Or you got a case of white man’s disease.
The knack of always saying the wrong thing. The expression is both a verbal play on the foot-and-mouth disease that affects livestock and on the expression “to put one’s foot in one’s mouth,” meaning to make a verbal blunder. The latter dates from the late nineteenth or early twentieth century (see also put one’s foot in it). The current cliché is much newer, dating from the mid-twentieth century.