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Hemophilia (or haemophilia) B, a blood-clotting disorder in which a mutation of the Factor IX gene leads to a deficiency of Factor IX (or Christmas factor), a serine protease of the coagulation system. Both the factor and the disease are named for Stephen Christmas (not the holiday), the first patient discovered to have the condition in 1952. We haven't let our daughter participate in any more physical sports since she was diagnosed with Christmas disease last year.
desperate diseases must have desperate remedies
Extreme and undesirable circumstances or situations can only be resolved by resorting to equally extreme actions. I know that the austerity measures introduced by the government during the recession are unpopular, but desperate diseases must have desperate remedies.
the disease to please
A constant need to make others happy. I think you're miserable because you have the disease to please. Try doing what makes you happy instead.
Desperate diseases must have desperate remedies.
Prov. If you have a seemingly insurmountable problem, you must do things you ordinarily would not do in order to solve it. Fred: All my employees have been surly and morose for months. How can I improve their morale? Alan: Why not give everyone a raise? Fred: That's a pretty extreme suggestion. Alan: Yes, but desperate diseases must have desperate remedies.
(the) disease to please
an obsessive need to please people. I, like so many, am afflicted with the disease to please. I am just too nice for my own good.
*down with a disease
ill; sick at home. (Can be said about many diseases. *Typically: be ~; Come ~; get~.) Tom isn't here. He's down with a cold. Sally is down with the flu.
the tendency to say the wrong thing at the wrong time. I suffer a lot from foot-in-mouth disease. Well, Ralph has foot-in-mouth disease again.
See also: disease
shake a disease or illness off
Fig. [for the body] to fight off a disease or illness. I thought I was catching a cold, but I guess I shook it off. I hope I can shake off this flu pretty soon.
foot in one's mouth, put one's
Say something foolish, embarrassing, or tactless. For example, Jane put her foot in her mouth when she called him by her first husband's name. This notion is sometimes put as having foot-in-mouth disease, as in He has a bad case of foot-in-mouth disease, always making some tactless remark. The first expression dates from about 1900. The variant, dating from the mid-1900s, is a play on the foot-and-mouth (sometimes called hoof-and-mouth) disease that afflicts cattle, causing eruptions to break out around the mouth and hoofs.
the British diseasea problem or failing supposed to be characteristically British, especially (formerly) a proneness to industrial unrest. informal
n. the tendency to say the wrong thing at the wrong time. Well, Ralph has foot-in-mouth disease again.
See also: disease
white man’s disease
n. the inability to jump in basketball. You break your leg, Walter? Or you got a case of white man’s disease.