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1. To squeeze something out (of something else). A noun or pronoun can be used between "crush" and "out." This hat is too tight—it's crushing my brains out! This kind of juicer chews up the fruit and vegetables before crushing out their juice.
2. To extinguish something by crushing it, especially a cigarette. A noun or pronoun can be used between "crush" and "out." I took one last drag and crushed the cigarette out in the ashtray. The detective crushed out his cigarette angrily and stormed out of the room.