1. A spiritual meeting in which participants are encouraged to repent their sins and accept Jesus Christ as their savior. I've told her that I am an avid atheist, but she still insists on me attending one of her come-to-Jesus meetings.
2. Any meeting in which a frank, often unpleasant, conversation is held so as to bring to light and/or resolve some issue at hand. Boys, we're going to have a come-to-Jesus meeting about the drugs I found in the house, and if no one tells me the truth, then you're both going to get a whooping. The boss called us in for a real come-to-Jesus meeting about our sales for this quarter.
See also: meeting