1. To muddle, confuse, or ruin something. A noun or pronoun can be used between "ball" and "up." Boy, I really balled up the directions—where are we? Here are the items I need from the grocery store—don't ball it up!
2. To roll or form into a ball. I balled up my clothes and threw them in the hamper.
3. To cause someone to become confused or flummoxed. In this usage, a noun or pronoun can be used between "ball" and "up." Missing the last page of the directions really balled me up—that's why I'm late.
*(all) balled up
troubled; confused; in a mess. (*Typically: be ~; get ~.) John is all balled up because his car was stolen.
mod. confused; mixed up. (This is hyphenated before a nominal.) That dame is so balled up she doesn’t know anything.