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1. In medicine, a liquid solution that contains one or more radioactive elements, which is swallowed orally and used in the diagnosis or treatment of disorders, especially cancer and diseases of the thyroid. We are just going to administer a sort of atomic cocktail to track the disease's progress. That way, we can better gauge what course of action to take.
2. An alcoholic drink composed of vodka, brandy, champagne, and sherry. Created in Las Vegas, Nevada, and named after the nuclear tests conducted in the state during the 1950s. Barkeep, I want something that will knock my socks off. Fix me an atomic cocktail!
slang A very severe wedgie, a maneuver in which someone's underwear is yanked up from behind until it is wedged between their buttocks, typically as a prank. Come on, let's give that nerd an atomic wedgie!
n. an instance of pulling someone’s underpants up very tightly—from the rear—so that the cloth is pulled between the victim’s buttocks; a severe wedgie or melvin. I’m going to sneak up behind Bob and give him an atomic wedgie.