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afflict (one) with

1. To cause one to contract an ailment or disease. A person's name or pronoun can appear before "with." My classroom has been almost empty all week because one kid afflicted the others with chicken pox. When you have a child in preschool, you'll be afflicted with every illness.
2. To cause another person hardship or difficulty. When used in this sense, a noun or pronoun typically does not appear between "afflict" and "with." Once I finally recovered from my illness, I was afflicted with medical bills.
3. To force someone to spend time with an irritating person. A person's name or pronoun typically appears before "with." Please don't afflict me with your obnoxious brother this evening.
See also: afflict

afflict someone with someone

to burden someone with an annoying person. I was foolish enough to afflict myself with my young cousin for the weekend.
See also: afflict

afflict someone with something

1. Lit. to cause someone to suffer from a disease or disability. The virus has afflicted everyone in the valley.
2. Fig. to burden someone with trouble. We were afflicted with all the worry that comes with raising a teenager.
See also: afflict
References in periodicals archive ?
The respiratory infection, which can cause fever, night sweats, diarrhea, abdominal pain and wasting, afflicts an estimated one-fifth of all AIDS patients.
ALS afflicts about 20,000 people in the United States.
This trial represents a major step toward the development of an effective therapy for DMD, which is the most common and lethal genetic childhood disorder and which afflicts one in 3,500 boys.
The animal suffered from a type of pneumonia that often afflicts children with AIDS and from skin tumors that resemble those seen in Kaposi's sarcoma, the bluish-colored growths that often afflict people with AIDS.
Type 2 diabetes, a disease in which insulin resistance leads to elevated blood sugar levels, currently afflicts over 160 million people worldwide.
A new scientific report supports previous research indicating that cell therapy, a controversial treatment unlicensed by the federal government, provides no benefit to children with Down's syndrome, a genetic disorder that afflicts about one out of every 800 infants born in the United States.
Texas researchers have developed and tested a new fluoride and calcium therapy for spinal osteoporosis, a type of porous bone disease that afflicts 5 million people in the United States, predominantly elderly women.
Use of the newer immunosuppressive drugs has been controversial Atopic dermatitis is a very common skin disease that afflicts over 15 million Americans.
Chlamydia, which has been called the veneral disease of the '80s, is a bacterial infection that afflicts between 3 million and 10 million women and men in the United States each year, more than are afflicted by syphilis, herpes or gonorrhea.
This prospective ability of BDC-03 to preferentially shift overall weight gain in the form of lean muscle may well turn out to be a critically important therapeutic outcome for those suffering from cachexia, a deadly muscle wasting disease that afflicts 25% of all AIDS patients and upwards of 90% of all advanced cancer patients.
Obstructive Sleep Apnea (OSA) is a debilitating, often life-threatening condition that afflicts 18 million Americans.
The National Psoriasis Foundation estimates that psoriasis afflicts more than 7 million Americans and that between 150,000 and 260,000 new cases are diagnosed each year.