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afflict (one) with

1. To cause one to contract an ailment or disease. A person's name or pronoun can appear before "with." My classroom has been almost empty all week because one kid afflicted the others with chicken pox. When you have a child in preschool, you'll be afflicted with every illness.
2. To cause another person hardship or difficulty. When used in this sense, a noun or pronoun typically does not appear between "afflict" and "with." Once I finally recovered from my illness, I was afflicted with medical bills.
3. To force someone to spend time with an irritating person. A person's name or pronoun typically appears before "with." Please don't afflict me with your obnoxious brother this evening.
See also: afflict

afflict someone with someone

to burden someone with an annoying person. I was foolish enough to afflict myself with my young cousin for the weekend.
See also: afflict

afflict someone with something

1. Lit. to cause someone to suffer from a disease or disability. The virus has afflicted everyone in the valley.
2. Fig. to burden someone with trouble. We were afflicted with all the worry that comes with raising a teenager.
See also: afflict
References in periodicals archive ?
The group reports evidence that ancient Egyptians suffered from schistosomiasis, a disease that afflicts up to 300 million people around the globe.
Although CJD afflicts just 1 in 1 million people worldwide each year, the new cases have touched off a panic in Europe, prompting a widespread ban on imports of British beef and the decision to slaughter 11 million apparently healthy cattle in the United Kingdom.
Since then, the researchers have shown that NSP4 afflicts mice in much the same way that rotavirus afflicts mice-and humans.
ALS afflicts about 20,000 people in the United States.
Effective immediately, Ricerca will begin developmental work on PhytoMedical's BDC-03 compound for cachexia, a devastating muscle wasting condition that afflicts 25% of all AIDS patients and upwards of 90% of all advanced cancer patients.
The second son of Reed and his wife Terry was born in September of 1996 with Achondroplasia, a form of dwarfism that afflicts roughly 1 out of every 25,000 babies born in the United States.
The prospective capacity of BDC-03 to induce overall weight gain in the form of lean muscle mass has focused PhytoMedical's attention to the development of a new compound for the treatment of cachexia, a devastating condition that afflicts 25% of all AIDS patients and upwards of 90% of all advanced cancer patients.
A new scientific report supports previous research indicating that cell therapy, a controversial treatment unlicensed by the federal government, provides no benefit to children with Down's syndrome, a genetic disorder that afflicts about one out of every 800 infants born in the United States.
According to research published by The Sage Group, there is an overwhelming lack of awareness of PAD which afflicts 14-18 million Americans, compared to coronary artery disease and diabetes afflicting 12.
Working with InSite Clinical Trials and a pharmaceutical sponsor, Westlake Medical Research is evaluating a medicine for osteoarthritis, a painful breakdown of cartilage in the joints that afflicts 16 million people nationwide.
This trial represents a major step toward the development of an effective therapy for DMD, which is the most common and lethal genetic childhood disorder and which afflicts one in 3,500 boys.
Texas researchers have developed and tested a new fluoride and calcium therapy for spinal osteoporosis, a type of porous bone disease that afflicts 5 million people in the United States, predominantly elderly women.