PM has been shown to activate
several vasoactive pathways, including the release of endothelins (Bouthillier et al.
HIV-I gp120 and chemokines activate
ion channels in primary macrophages through CCR5 and CXCR4 stimulation.
Strauss III of the University of Pennsylvania Medical Center in Philadelphia whose group reported last March that certain fragments of the clotting protein fibronectin activate
While DEHP acts through a PPAR-mediated pathway to exert its effects on the female reproductive system, other phthalates such as DBP may activate
only liver enzymes to alter steroid metabolism.
This release brings a new level of functionality for outsourcers and integration with cloud based service desk and hosted service desk products, making it even easier for service providers to integrate their service management solutions with Activate
on-premise provisioning and automation.
Assaying an unknown agent in parallel with tumor promoter TPA, EGF, or TNF[kappa] at their threshold concentrations for promotion of transformation will allow one to determine whether exposure to the unknown agent alone activates
transcription factor at levels that exceed transformation-relevant thresholds.
Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate
For example, polychlorinated biphenyls, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and o,p'-dichlorodiphenyltrichloroethane (o,p'-DDT) have been reported to activate
ERK and JNK in various types of cells (26-32).
The demonstration of a functional PPAR in human breast cancer cell lines that can bind specifically to a PPRE indicates that peroxisome proliferators may transcriptionally activate
peroxisome proliferator-regulated genes in human breast epithelial cells (53).
Geneticist En Li, now at Massachusetts General Hospital-East in Charlestown, says he and his co-workers showed for the first time that an embryo needs DNA methylation to selectively activate
Sachs and Guharay activate
the newly discovered channel, which they call the stretch-activated channel, by applying suction to a thin glass pipette attached to the cell membrane.