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ache for (someone or something)

1. To feel a strong desire for someone or something. She ached for the companionship of her husband when he was deployed overseas.
2. To feel profound sadness or empathy for someone. I ache for those little children who just lost their parents in a car accident.
See also: ache, for


1. verb To complain or gripe about someone or something. Of course Marjorie is bellyaching about how I left dishes out in the kitchen—she's not happy unless everything is perfectly put away.
2. noun Pain in one's stomach. I've had a bellyache all day, so I'm going to have to cancel our dinner plans.


Ill health caused by a hangover or alcohol withdrawal. If he just stops drinking all of a sudden, without medical supervision, he's liable to suffer from bottleache. I woke up with the worst bottleache of my life.
Farlex Dictionary of Idioms. © 2015 Farlex, Inc, all rights reserved.

ache for someone or something

 and hurt for someone or something
Fig. to desire someone or something very much. (So much that it "hurts.") Jim ached for the sight of Mary, whom he loved deeply.
See also: ache, for
McGraw-Hill Dictionary of American Idioms and Phrasal Verbs. © 2002 by The McGraw-Hill Companies, Inc.


(ˈbɛli ek)
1. n. a stomachache. Oh, mama, do I have a bellyache!
2. in. to complain. You are always bellyaching!


n. a hangover; the delirium tremens. I got a touch of the bottleache this morning.
McGraw-Hill's Dictionary of American Slang and Colloquial Expressions Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
AChE activity is therefore widely used in biomonitoring studies as a biomarker of OP pesticide exposure.
The effect of pH and temperature for purified AChE was determined by measuring the enzyme activities at the different pH using an overlapping buffer system consisting of acetate buffer (pH 4 to 6), potassium phosphate buffer (pH 6 to 8) and Tris-Cl (pH 7 to 9) and temperatures (15 to80C) for 10 min and enzyme activity was assayed withATC as previously described.
The effect of different parameters including concentration of chitosan, AChE, glutaraldehyde, DTNB, incubation time, the pH, and color intensity was examined to optimize the bioactive paper assay.
Having researched her aches and pains, she learned New Zealand green-lipped mussels contain an oil that helps ageing joints, but she didn't know how to source it - until now.
AChE enzyme is of extreme pharmacological and economic importance as it occurs as a chief CNS enzyme in insects and pests (Colovic et al., 2013; Kono and Tomita 2006).
Faculty have come from 15 different states, and the first ACHE classroom building was recognized for its architecture.
There's nothing like it, if you're lying in bed at three o'clock in the morning and you're getting this horrible cramping sensation." What's more, Len's wife also suffered with similar problems including aches and pains in her legs.
As the inhibition of AChE causes an increase in the concentration of ACh in cholinergic synapses, new and potent AChE inhibitors may be helpful in the treatment of AD [11].
Despite the fact that biperiden is used in therapy of parkinsonism, there is no evidence about possible interaction with AChE itself.
Acetylcholinesterase (AChE) is a key enzyme that hydrolyzes the neurotransmitter acetylcholine in cholinergic synapses of both vertebrates and invertebrates; this may affect a nerve's ability to conduct due to the accumulation of acetylcholine in the body once AChE is inhibited [3133].
At the end of anesthesia, anticholinesterase drugs such as neostigmine are recommended to reverse the residual neuromuscular block, which has a high incidence rate and can lead to critical respiratory events.[sup][1],[2] Cholinesterase can be divided into two categories: acetylcholinesterase (AChE) and pseudocholinesterase.
has been contracted by a tier one US defense contractor as the primary supplier of Recombinant Human Acetylcholinesterase (AChE) in support of a Program of Record chemical warfare disclosure spray.
Global Markets Direct's, 'Ache Laboratorios Farmaceuticos S/A - Product Pipeline Review - 2016', provides an overview of the Ache Laboratorios Farmaceuticos S/A's pharmaceutical research and development focus.