aching

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ache for

1. To feel a strong desire for someone or something. She ached for the companionship of her husband when he was deployed overseas.
2. To feel sadness and/or empathy for someone. I ache for those little children who just lost their parents in a car accident.

aching heart

A feeling of pain or despair in the absence of someone one loves. I had such an aching heart during the holidays this year, the first ones without my mother.
See also: aching, heart

ache for someone or something

 and hurt for someone or something
Fig. to desire someone or something very much. (So much that it "hurts.") Jim ached for the sight of Mary, whom he loved deeply.

aching heart

Fig. the feeling of pain because of love that is lost or has faded away. (Described as being in the heart, where love is said to reside.) I try to tell my aching heart that I don't love him.
See also: aching, heart
References in periodicals archive ?
As shown in [Figure 2], AChE staining was detected at motor endplate regions in rat diaphragms from both the sham and the septic groups.
Evaluate Ache Laboratorios Farmaceuticos S/A's strategic position with total access to detailed information on its product pipeline
In this study, a significant difference was found between males and females for neck ache (P=0.
HPTLC Screening for Inhibitors of AChE and BuChE: Direct Bioautography (DB) Technique.
In this study, a reduction in the AChE activity by malathion, dichlorvos and temephos were observed in brain, liver, kidney and gill after 40 days of exposure compared to the control.
2004) first reported the promising potential of non-nitrogenous natural compounds including xanthones as AChE inhibitors.
AChE activity measurement in different diazinon concentrations (50, 100, 200, 300 and 400 ug L-1) is presented in Table I.
The effect of pH and temperature for purified AChE was determined by measuring the enzyme activities at the different pH using an overlapping buffer system consisting of acetate buffer (pH 4 to 6), potassium phosphate buffer (pH 6 to 8) and Tris-Cl (pH 7 to 9) and temperatures (15 to80C) for 10 min and enzyme activity was assayed withATC as previously described.
The cells were seeded in 6-well-plates at 500,000 cells/well 24 hr before exposure to dioxin or other chemical treatment for determiniation of AChE activity.
Ache is owned by the Baptista, Siaulys and the Depieri families.
3 April 2013 - Pharmaceutical majors Pfizer Inc (NYSE:PFE) Novartis AG (VTX:NOVN) and Abbott Laboratories (NYSE:ABT) could make second-round offers to buy Brazil's Ache Laboratorios Farmaceuticos, with the deadline for bids set in the second part of this month, informed people told Reuters.
If patients are going to develop muscle ache when on statin therapy, it can happen after taking the medication at least after one month.
The usual age of onset is between 3 and 6 months of age, but infantile ache may occur anywhere from 0 to 12 months of age (hence, the potential for overlap in the presentation of neonatal and infantile acne) and occasionally up to 16 months of age.
M2 PHARMA-April 19, 2011-Oxford Nutrascience, Brazilian Ache seal exclusive licensing and distribution deal(C)2011 M2 COMMUNICATIONS