screw up the works

To interfere with the proper functioning of something. Oh, come on! More regulations will just screw up the works.

See also:

screw (something) into (something)
screw into
screw around with
screw around with someone or something
screw in
a turn of the screw
turn of the screw
have a loose screw
have a screw loose
screw loose, to have a

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