be driven mad

1. To be made mentally unstable. In the play, the king is driven mad by the specter of his murdered brother. Most people reckon she was driven mad by the trauma of what happened. I hate this, I feel like I'm being driven mad by grief.

2. To be upset, irritated, or annoyed as if to the point of mental disturbance. Will you please take the kids out of the house while I finish this report? I'm being driven mad by all the noise! We're being driven mad by our neighbor's incessant drumming! That's it, I'm officially being driven mad by all of this mindless data entry work.