What's up doc?

What's up, doc?

What's new? What's happening with you? Popularized by—and now almost solely associated with—the Looney Tunes character Bugs Bunny. A: "What's up, doc?" B: "I really wish you wouldn't say that every time we see each other, Dad. It's so dorky." Every time my little sister is eating a carrot, she turns to me and says, "Ehh, what's up, doc?"
Farlex Dictionary of Idioms. © 2015 Farlex, Inc, all rights reserved.

What’s up doc?

interrog. What is happening here? What’s up doc? How’re things going?
See also: up
McGraw-Hill's Dictionary of American Slang and Colloquial Expressions Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.