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Under no circumstances; I will not permit it; absolutely not. A: "Mom, can I borrow the car this Saturday?" B: "After the dent you left in it the last time? Nothing doing!"
Inf. I will not permit it!; I will not participate in it! John: Can I put this box in your suitcase? Bill: Nothing doing! It's too heavy now. Sue: We decided that you should drive us to the airport. Do you mind? Jane: Nothing doing! I've got work to do.
exclam. No!; I refused to do it! Me, go to the opera? Nothing doing!