with a screw loose

with a screw loose

Having or characterized by silliness, eccentricity, craziness, or mental instability. There's some guy with a screw loose standing on the corner yelling obscenities at passersby. I have this strange fear that I'm going to turn into a lonely old bachelor with a screw loose when I get old.
See also: loose, screw
References in classic literature ?
The man who doesn't believe in ROBINSON CRUSOE, after THAT, is a man with a screw loose in his understanding, or a man lost in the mist of his own self-conceit