vaccinate

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vaccinate (someone or an animal) against something

to inoculate or immunize someone or an animal against some disease. They had to vaccinate us against yellow fever. The vet vaccinated the horse against everything that threatened it.
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vaccinate (someone or an animal) with something

to inoculate or immunize someone or an animal with some substance. This time the doctor vaccinated Tom with killed virus. The vet vaccinated the cat with something that would prevent rabies.
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vaccinate against

or vaccinate for
v.
To give someone a vaccination to produce immunity to some infectious disease: The doctor vaccinated the child against measles. The dog has been vaccinated for rabies.
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vaccinated with a Victrola needle

Someone who chatters incessantly. Victrola, a division of R.C.A. Victor, was a brand of phonograph players. Since phono records were played with needles that picked up the sound vibrations in the record's grooves, to be vaccinated with a Victrola needle, as the joke implied, was to be inoculated with the gift of nonstop gab.
See also: needle, vaccinate