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to become exhausted. I tire out easily. When I had the flu, I found that I tired out easily.
tire someone out
to exhaust someone. The extra work tired him out a lot. Too much work will tire out the horses.
tire you out
to feel that you do not have any energy Painting the living room in one day really tired Dad out.
To deplete the strength or energy of someone or something; fatigue someone or something: Traveling always tires me out. The long ride tired out the horses.