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Related to tangles: Neurofibrillary tangles

tangle someone or something up

to entangle someone or something. Please don't tangle me up in your ropes. I tangled up my feet in the cords on the floor.
See also: tangle, up

tangle with someone or something (over someone or something)

to battle against someone or something about someone or something. Tim tangled with Karen over the children. I hope I don't have to tangle with the bank over this loan. I don't want to tangle with city hall.
See also: tangle

tangle with somebody/something

to disagree or fight with someone or something She's not afraid to tangle with her father. The two computer giants had tangled with each other in court several times.
Etymology: based on the literal meaning of tangle (to get things mixed together so that it is difficult to separate them)
See also: tangle

tangle up

1. To mix something together or intertwine it in a confused mass; snarl something: I accidentally tangled that rope up with the others. You've tangled up all the paper clips and now I can't separate them. The telephone cord is tangled up in a knot.
2. To catch and hold something in or as if in a net; entrap something: The children tangled the kite up in the branches. I tangled up the fishing lure as I was pulling it through the weeds. A dolphin became tangled up in the fishing net.
3. To involve someone in awkward or unsavory circumstances. Used chiefly in the passive: How did a good kid like you get tangled up with criminals? No politician would want to be tangled up in this sordid affair.
See also: tangle, up

tangle with

To enter into argument, dispute, or conflict with someone or something: The tenants were afraid to tangle with their landlord's expensive lawyers.
See also: tangle

tangle with someone/something

in. to quarrel or fight with someone or something. It’s like tangling with a grizzly.
See also: tangle
References in periodicals archive ?
Washington, May 8 ( ANI ): Greater purpose in life may help stave off the harmful effects of plaques and tangles associated with Alzheimer's disease.
Tangles Salon, located in Newburgh NY, selected Cool Life Systems to provide a range of services including the development and recent launch of the Tangles Salon website (http://www.
Images of the brain showed that the drug had its biggest effect in the parts of the brain linked to memory, where the density of tau tangles is greatest.
Until recently, plaques and tangles could be assessed only at autopsy or, rarely, on biopsy.
Compared with normal brains, the MCI brains showed significantly more tangles in the inferior parietal lobule, amygdala, entorhinal cortex, and subiculum.
According to Richard Zawitz, the inventor of Tangle and CEO of Tangle Creations, "Tangles are reusable, affordable and can easily be incorporated into all sorts of teacher-directed games and activities.
William Stewart, from the University of Glasgow and Southern General Hospital in Glasgow, UK, found both tau tangles and amyloid-beta plaques in survivors, years after a single moderate-to-severe TBI.
Tangles is so modern and progressive," responded Davis of her reasoning for accepting her new position with Tangles.
Bristles that don't hit tangles don't spin and are always brushing.
Dr Calum Sutherland and his team at Dundee University found the protein, called CRMP2, plays an important role in the development of nerve tangles seen in the disease.
What's more, removing amyloid rubbed out its partner in crime, a protein called tau that collects in tangles inside brain cells.
If your hair's a knotty mess don't try and smooth it out using a comb which will make the tangles tighter, leading to breakage.
TORONTO -- The [beta]-amyloid senile plaques and neurofibrillary tangles that are definitive for a diagnosis of Alzheimer's disease can now be identified without the need for brain biopsy specimen.
Mice with Human Tau Develop Tangles, Suffer Neuronal Death, Just Like Human Alzheimer's Disease Sufferers
Washington, Dec 4 (ANI): In a new study, scientists found that dynamic regulation of the chaperone protein Hsp27 is required to get rid of abnormally accumulating tau in the brains of mice genetically modified to develop the memory-choking tau tangles associated with Alzheimer's disease.