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bent on a splice

An older sailing phrase meaning about to or intending to get married. "Bent" in this context means determined or set (on a course of action), and "splice" refers to two ropes that have been joined to create a single, larger one. I can't wait for this voyage to be over, for I'm bent on a splice to my lady as soon as we reach home.
See also: bent, splice

splice the mainbrace

nautical To issue and partake in an extra ration of alcoholic spirits, especially rum or grog, amongst members of crew aboard a sea vessel. (The mainbrace, also spelled "main brace," is a brace attached to the main yard on sailing ships. "Splicing the mainbrace" was originally the very difficult job of repairing this brace, one which earned the repairman an extra ration of spirits; eventually, this euphemistic secondary meaning became the primary one.) As part of the celebrations for her Diamond Jubilee, the Queen gave the order to all in the Royal Navy to splice the mainbrace as a gesture of good cheer.
See also: splice

splice something (in)to something

to connect something to something; to cut and join something into something to connect the two. The workers spliced the small wires into the main cable. Let's splice this rope into the larger one at the halfway point.
See also: splice

splice something together

to connect things together, usually by twisting or tying a joint between the two. I spent over an hour splicing the two ends of the ropes together, and it didn't hold for even a minute. He carefully spliced together the two ropes.
See also: splice, together
References in periodicals archive ?
In this study, we demonstrate that the minisequencing-based tag-microarray system routinely used in our laboratory for multiplexed genotyping of single-nucleotide polymorphisms (20,21) can be adapted to multiplex detection of alternatively spliced transcripts.
We included 19 genes, with altogether 61 known alternatively spliced transcripts, in the assay panel (see Table 51 in the Data Supplement that accompanies the online version of this article at http: //www.
Each alternatively spliced transcript was amplified in an individual PCR reaction.
We established a 4-color microarray-based minisequencing system for multiplexed screening for alternatively spliced transcripts.
For most genes, minisequencing primers that anneal immediately adjacent to a splice junction were used, followed by extension of the primer with fluorescently labeled nucleotides that define the alternatively spliced transcripts, as exemplified in Fig.
Thus, a 4-color fluorescence signal pattern will be generated on the microarray to detect each of the 61 alternatively spliced variants.
In the endothelial cell lines, the number of detected alternatively spliced transcripts was lower, 31 (51%), presumably because the cancerrelated genes are not expressed or are expressed at lower concentrations in the endothelial cell lines.
For 385 (90%) of the 427 alternatively spliced transcripts screened for by the minisequencing system, the size analysis verified our results, either positive or negative.
In this study, we show that the tag-microarray minisequencing system originally developed for multiplexed genotyping of single-nucleotide polymorphisms (20, 21) can be adapted for multiplexed detection of alternatively spliced transcripts.
Thus, in PCR-based methods, the measured signals reflect the relative amount of PCR product corresponding to each splice variant, rather than the relative abundance of the alternatively spliced transcripts from each gene in the original sample.
Internal diagnostic projects include a prostate cancer diagnostic test, based on alternatively spliced isoforms of PSA and KLK2, and a blood-based diagnostic test for colon cancer.