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A rhetorical question meant to express that one is indifferent to or finds no importance in what's being discussed. So what if you don't finish high school? Plenty of people drop out and go on to have great lives. John: "You've got a lot of great qualities; any woman would be mad not to think you're a catch!" Dave: "So what? Sarah was the only girl for me, and now she's gone forever."
it does not seem important She's got a big career and yeah, she has a voice, so what? Maybe he's a little obnoxious sometimes, but so what?
Who cares? What does it matter? For example, You're not going to the beach today? Well, so what, you can go tomorrow, or So what if she left without saying goodbye-she'll call you, I'm sure. [First half of 1900s] Also see what of it.