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sick and tired of (something)
Exceedingly wearied by, bored of, or exasperated with something. I'm sick and tired of doing my boss's errands. If something doesn't change soon, I'm going to quit! I was all gung-ho about this graduate program when I first began, but I must admit that I've grown sick and tired of these boring lectures.
sick of (someone or something)
Thoroughly annoyed or exasperated by someone or something. I am so sick of all these political campaign ads. They're on all the time each election, and every year they get nastier and nastier. I got the feeling that he was getting pretty sick of me by the end of the day. I'm just sick of feeling so tired all the time.
*sick (and tired) of someone or something
Fig. tired of someone or something, especially something that one must do again and again or someone or something that one must deal with repeatedly. (*Typically: be ~; become ~; get ~; grow ~.) I am sick and tired of cleaning up after you. Mary was sick of being stuck in traffic.