1. [for someone] to run along, puffing to breathe. Sam puffed along, jogging on his morning route. As Wally puffed along, he thought again about going on a diet.
2. [for an engine] to move along, putting out puffs of smoke or steam. The old engine puffed along, driving the small boat slowly up the river. The locomotive puffed along, not making very much headway up the hill.
See also: puff