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powder one's noseand powder one's face
to depart to the bathroom. (Usually said by women, or jocularly by men.) Excuse me, I have to powder my nose. She just went out to powder her face.
powder your nose(spoken)
to use a public toilet “I'm going to powder my nose,” Vera said, following Elise out of the room.
Usage notes: usually said by women
powder your nose(humorous)
if a woman says she is going to powder her nose, she means she is going to go to the toilet Well, if you'll excuse me a moment, I'm going to powder my nose.